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Thus serum creatinine is a late marker of acute kidney injury. Enalapril therapy decreased albumin excretion from It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards.

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Therapeutic blockade of RAS slows the disease progression not only by hemodynamic action but also by induction of profibrotic agents. Later this study was done on diabetic patients with normal blood pressure and normoalbuminuria.

Third, microalbuminuria has a lower predictive value for renal dysfunction because of the high mortality rate caused by cardiovascular disease [ 78 ].

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Cystatin C concentration may be affected by the presence of cancer, thyroid disease, and smoking. Pregnancy must be excluded in any female of child-bearing age before this test is carried out. Progressive renal decline PRD Diabetic nephropathy has several phenotypes according to clinical and laboratory data; among them, PRD is the most serious. In other scenarios, renal function tests may be required to establish and monitor renal function where a known or possibly nephrotoxic therapeutic agent is to initiated for patient management. Renal function tests are also indicated in those individuals who are transplant donors to assess the initial donor suitability, and after that, to detect any significant deterioration of renal function post-donation. Introduction Diabetes is often accompanied by chronic kidney disease CKD and accounts for more than half of the cause of end-stage renal disease ESRD and dialysis [ 1 ]. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.

Urea may be decreased in starvation, low-protein diet, and severe liver disease. Kidney Int Rep.

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Finally, experimental overexpression of VEGF in adult mice replicates several aspects of diabetic kidney disease [ 41 ].

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Proteinuria (Albuminuria)